Article
hASH1 expression is closely correlated with endocrine phenotype and differentiation extent in pulmonary neuroendocrine tumors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 2004
Jiang Shi-Xu, Kameya Toru, Asamura Hisao, Umezawa Atsuko, Sato Yuichi, Shinada Jun, Kawakubo Yasuaki, Igarashi Toru, Nagai Kanji, Okayasu Isao
Abstract excerpt
The human homolog 1 of the Drosophila neurogenic achaete-scute genes, hASH1, is specifically expressed in fetal pulmonary neuroendocrine cells and in some neuroendocrine tumor cell lines. However, no data have been gathered regarding its in vivo expression in tumors. hASH1 mRNA expression was investigated by in situ hybridization in 238 surgically resected lung carcinomas, and the correlations between hASH1...
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