Article
Growth Hormone Stimulates Proliferation of Old–Aged Regenerating Liver Through Forkhead Box M1b
25 Nov 2003
Abstract excerpt
The Forkhead Box (Fox) proteins are an extensive family of transcription factors that shares homology in the winged helix DNA-binding domain and the members of which play essential roles in cellular proliferation, differentiation, and longevity. Reduced cellular proliferation during aging is associated with a progressive decline in both growth hormone (GH) secretion and Foxm1b expression. Liver regeneration...