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Infection and Injury of Neurons by West NileEncephalitisVirus

25 Nov 2003

Abstract excerpt

West Nile virus (WNV) infects neurons and leads to encephalitis, paralysis, and death in humans, animals, and birds. We investigated the mechanism by which neuronal injury occurs after WNV infection. Neurons in the anterior horn of the spinal cords of paralyzed mice exhibited a high degree of WNV infection, leukocyte infiltration, and degeneration. Because it was difficult to distinguish whether neuronal injury...

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PMID: 14645577
DOI: 10.1128/jvi.77.24.13203-13213.2003

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