Article
Genetic evolution of alpha fetoprotein producing gastric cancer.
Journal of clinical pathology - 1 Dec 2003
Fujii H, Ichikawa K, Takagaki T, Nakanishi Y, Ikegami M, Hirose S, Shimoda T
Abstract excerpt
BACKGROUND: Alpha fetoprotein (AFP) producing gastric cancer is an unusual form of aggressive adenocarcinoma with a complex histological picture, including enteroblastic and hepatoid differentiation. AIMS: To investigate the genetic events underlying the phenotypic diversity in AFP producing gastric cancer and the ability of these tumours to produce AFP ectopically. METHODS: Multiple foci from 19 AFP producing...
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