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Article

1H NMR studies of the effect of mutation at Valine45 on heme microenvironment of cytochrome b5.

Biochimie - 1 Oct 2003

Cao Chunyang, Zhang Qi, Wang Zhi-Qiang, Wang Yue-Feng, Wang Yun-Hua, Wu Houming, Huang Zhong-Xian

Abstract excerpt

1D and 2D (1)H NMR were employed to probe the effects on the heme microenvironment of cytochrome b(5) caused by the mutation from Val45 to Tyr45, His45 and Glu45. Compared with wild type (WT) cytochrome b(5), in all mutants the heme ring are CCW rotated relative to the imidazole planes of axial ligands and the angles beta between two axial ligand imidazole planes are not changed, being in agreement with the...

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Identifiers

PMID: 14644556
DOI: 10.1016/j.biochi.2003.08.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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