Article
Dynamic effects of mutations within two loops of cytochrome c551 from Pseudomonas aeruginosa.
Proteins - 1 Feb 2003
Ceruso Marc Antoine, Grottesi Alessandro, Di Nola Alfredo
Abstract excerpt
In this work, we investigated the structural and dynamic consequences of two substitutions, P58A and G36P, located in two different solvent-exposed loops of cytochrome c551. The results show that both mutations affect regions that are distant from the site of mutation. Here, the two loops appear to be dynamically coupled to each other, because the substitution at one site affects the structure and the dynamics of...
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