Article
Tissue factor and platelet glycoprotein Ib-alpha alleles are associated with age at first coronary bypass operation.
Anesthesiology - 1 Dec 2003
Donahue Brian S, Byrne Daniel W, Gailani David, George Alfred L
Abstract excerpt
BACKGROUND: Age is a known risk factor for postoperative complications, but the genetic factors that account for variability in age at presentation for surgery have not been characterized. Because thrombosis is a critical process in the development of coronary syndromes, the authors hypothesized that patients bearing the -1208 insertion allele of tissue factor (TF) and longer glycoprotein Ib-alpha (GpIbalpha)...
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