Article
Parental allergic status influences the risk of developing allergic sensitization and an asthmatic-like phenotype in canine offspring.
Immunology - 1 Dec 2003
Barrett Edward G, Rudolph Karin, Bowen Larry E, Bice David E
Abstract excerpt
Increasing evidence suggests that parental allergic status, especially that of the mother, may play a unique and important role in influencing the development of fetal infant immune responses to inhaled allergens, independently of genetic predisposition. We have developed an experimental model in dogs where the offspring from allergic parents, when exposed to inhaled allergen, develop allergic sensitization and...
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