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Article

Duration of allergic susceptibility in maternal transmission of asthma risk.

American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Aug 2007

Fedulov Alexey V, Leme Adriana S, Kobzik Lester

Abstract excerpt

PROBLEM: Asthma has its origins in early-life. Maternal, not paternal asthma is an important risk factor, but the mechanisms and the duration of the maternal effect are unknown. METHOD OF STUDY: Offspring of asthmatic and normal mice were sensitized with ovalbumin (OVA) at 1, 3, 6 and 10 weeks of age, challenged with aerosolized OVA 2 weeks later and tested for airway hyperresponsiveness (AHR) and allergic airway...

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Source

Identifiers

PMID: 17631005
DOI: 10.1111/j.1600-0897.2007.00496.x

Genes

AHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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