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Article

Alternative promoters regulate transcription of the gene that encodes stem cell surface protein AC133

25 Nov 2003

Abstract excerpt

AC133 is a member of a novel family of cell surface proteins with 5 transmembrane domains. The function of AC133 is unknown. Although AC133 mRNA is detected in different tissues, its expression in the hematopoietic system is restricted to CD34+ stem cells. AC133 is also expressed on stem cells of other tissues, including endothelial progenitor cells. However, despite the potential importance of AC133 to the field...

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PMID: 14630820
DOI: 10.1182/blood-2003-06-1881

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