Article
[The properties of the cellular surface of Yersinia pestis strain EV and its achromogenic variants].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Zadnova S P, Shcherbakov A A, Diatlov I A, Kukleva L M, Protsenko O A, Kononov N P
Abstract excerpt
The comparative study of the properties of the surface of vaccine strain Y. pestis EV and its achromogenic variants (AV) differing from the initial strain by decreased immunogenicity and by the morphology of colonies, has been made. The achromogenicity of Y. pestis colonies has been shown to correlate with the loss of the outer membrane protein with a molecular weight 22 kD. The synthesis of this protein is...
Topics
- Animals
- Bacterial Adhesion
- Bacterial Outer Membrane Proteins
- Electrophoresis, Polyacrylamide Gel
- Erythrocytes
- Genetic Variation
- Guinea Pigs
- Humans
- Macrophages, Peritoneal
- Mice
- Phagocytosis
- Plague Vaccine
- Selection, Genetic
- Sheep
- Surface Properties
- Vaccines, Attenuated
- Yersinia pestis