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Article

A WW domain binding region in methyl-CpG-binding protein MeCP2: impact on Rett syndrome.

Journal of molecular medicine (Berlin, Germany) - 1 Feb 2004

Buschdorf Jan P, Strätling Wolf H

Abstract excerpt

Rett syndrome is a dominant neurological disorder caused by loss-of-function mutations of methyl-CpG-binding protein 2 (MeCP2). MeCP2 is an abundant chromatin-associated protein that contains two well characterized domains. Through an N-terminal domain it recognizes methyl-CpGs and binds to nonmethylated DNA. A domain in the middle of the protein can act as a transcriptional repressor in transient transfection...

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Source

Identifiers

PMID: 14618241
DOI: 10.1007/s00109-003-0497-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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