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Article

Insulin-like growth factor-II gene polymorphism is associated with primary open angle glaucoma.

Journal of clinical laboratory analysis - 1 Jan 2003

Tsai Fuu-Jen, Lin Hui-Ju, Chen Wen-Chi, Chen Huey-Yi, Fan Seng-Sheen

Abstract excerpt

Hypoxia and ischemia play important roles in the onset and progression of glaucoma. Insulin-like growth factors (IGF) are important neurotrophic agents that respond to hypoxia-ischemia. In this study, we enrolled 60 primary open angle glaucoma (POAG) patients and 104 healthy volunteers from the China Medical College Hospital. Among the polymorphism of IGFs gene, exon 9 Apa I C/T gene polymorphism is the most...

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Identifiers

PMID: 14614750
DOI: 10.1002/jcla.10106
PMCID: PMC6808164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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