Article
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells.
The Journal of cell biology - 10 Nov 2003
Xiao Kanyan, Allison David F, Buckley Kathleen M, Kottke Margaret D, Vincent Peter A, Faundez Victor, Kowalczyk Andrew P
Abstract excerpt
The mechanisms by which catenins regulate cadherin function are not fully understood, and the precise function of p120 catenin (p120ctn) has remained particularly elusive. In microvascular endothelial cells, p120ctn colocalized extensively with cell surface VE-cadherin, but failed to colocalize with VE-cadherin that had entered intracellular degradative compartments. To test the possibility that p120ctn binding...
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