Article
Role of the DGAT gene C79T single-nucleotide polymorphism in French obese subjects.
Obesity research - 1 Oct 2003
Coudreau Sylvie Kipfer, Tounian Patrick, Bonhomme Geneviève, Froguel Philippe, Girardet Jean-Philippe, Guy-Grand Bernard, Basdevant Arnaud, Clément Karine
Abstract excerpt
Acyl-coenzyme A, diacylglycerol acyltransferase (DGAT), is a key enzyme involved in adipose-cell triglyceride storage. A 79-bp T-to-C single-nucleotide polymorphism (SNP) on the 3' region of the DGAT transcriptional site has been reported to increase promoter activity and is associated with highe...
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