Article
F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation.
Cell - 17 Oct 2003
Hu Qi-Dong, Ang Beng-Ti, Karsak Meliha, Hu Wei-Ping, Cui Xiao-Ying, Duka Tanya, Takeda Yasuo, Chia Wendy, Sankar Natesan, Ng Yee-Kong, Ling Eng-Ang, Maciag Thomas, Small Deena, Trifonova Radianna, Kopan Raphael, Okano Hideyuki, Nakafuku Masato, Chiba Shigeru, Hirai Hisamaru, Aster Jon C, Schachner Melitta, Pallen Catherine J, Watanabe Kazutada, Xiao Zhi-Cheng
Abstract excerpt
Axon-derived molecules are temporally and spatially required as positive or negative signals to coordinate oligodendrocyte differentiation. Increasing evidence suggests that, in addition to the inhibitory Jagged1/Notch1 signaling cascade, other pathways act via Notch to mediate oligodendrocyte di...
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