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Article

Genetic basis of congenital generalized lipodystrophy.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Feb 2004

Agarwal A K, Barnes R I, Garg A

Abstract excerpt

Congenital generalized lipodystrophy (CGL) is an autosomal recessive disorder characterized by extreme lack of body fat and severe insulin resistance since birth. Recently, mutations have been reported in 1-acylglycerol-3-phosphate-O-acyltransferase 2 (AGPAT2) and Berardinelli-Seip congenital lipodystrophy 2 (BSCL2 or Seipin) genes in affected subjects from pedigrees linked to chromosomes 9q34 and 11q13,...

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Source

Identifiers

PMID: 14557833
DOI: 10.1038/sj.ijo.0802487

Genes

AGPAT2
BSCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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