Article
[Recent data on the physiopathology of hyperthyroidism].
Bulletin de l'Academie nationale de medecine - 1 Jan 2003
Milgrom Edwin
Abstract excerpt
Cloning of the TSH receptor has led to marked progress in the understanding of the pathogenesis of hyperthyroidism. Genetic studies in familial cases of Graves disease have allowed to dismiss the TSH receptor as a candidate gene. Loci harbouring genes probably involved in the occurrence of Graves' disease have been described. Purification of native TSH receptor has allowed to study directly and to characterize...
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