Article
The MUC5AC Glycoprotein is the Primary Receptor for <i>Helicobacter pylori</i> in the Human Stomach
1 Oct 2003
Abstract excerpt
BACKGROUND AND OBJECTIVES: Helicobacter pylori shows a characteristic tropism for the mucus-producing gastric epithelium. In infected patients, H. pylori colocalizes in situ with the gastric secretory mucin MUC5AC. The carbohydrate blood-group antigen Lewis B (LeB) was deemed responsible for the adherence of H. pylori to the gastric surface epithelium. We sought to determine if MUC5AC is the carrier of LeB, and...
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