Article
Maspin in thyroid cancer: its relationship with p53 and clinical outcome.
Oncology reports - 1 Jan 2000
Boltze Carsten, Schneider-Stock Regine, Meyer Frank, Peters Brigitte, Quednow Claudia, Hoang-Vu Cuong, Roessner Albert
Abstract excerpt
The serine protease inhibitor maspin has been reported to inhibit invasiveness and motility of tumor cells. Additionally, a p53-dependent regulatory pathway of maspin in human cancer has been indicated. In a pre-study we were able to detect maspin protein in papillary thyroid carcinomas (PTC), wh...
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