Article
Comparison of the myotonic dystrophy associated CTG repeat in European and Japanese populations.
Journal of medical genetics - 1 Nov 1992
Davies J, Yamagata H, Shelbourne P, Buxton J, Ogihara T, Nokelainen P, Nakagawa M, Williamson R, Johnson K, Miki T
Abstract excerpt
Gene amplification using polymerase chain reaction (PCR) was carried out on DNA samples from a total of 92 normal subjects and 52 subjects with myotonic dystrophy (DM) from European and Japanese populations, to determine the copy number of the CTG repeat associated with DM for each group. In the...
Topics
- Alleles
- Base Sequence
- DNA Mutational Analysis
- Europe
- Female
- Gene Frequency
- Humans
- Japan
- Male
- Myotonic Dystrophy
- Pedigree
- Polymerase Chain Reaction
- Repetitive Sequences, Nucleic Acid