Vitamin D receptor initiation codon polymorphism, bone density and inflammatory activity of patients with ankylosing spondylitis.

doi:10.1007/s00198-003-1501-5

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Article

Vitamin D receptor initiation codon polymorphism, bone density and inflammatory activity of patients with ankylosing spondylitis.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Dec 2003

Obermayer-Pietsch Barbara M, Lange Uwe, Tauber Gerlinde, Frühauf Gerwig, Fahrleitner Astrid, Dobnig Harald, Hermann Josef, Aglas Ferdinand, Teichmann Joachim, Neeck Gunter, Leb Georg

Abstract excerpt

OBJECTIVES: Osteoporosis is a common finding in ankylosing spondylitis (AS) and may contribute to spinal deformity and bone pain. Bone metabolism as well as inflammatory processes are influenced by the vitamin D receptor gene (VDR). We investigated initiation codon ( FokI) and 3'UTR ( BsmI) polymorphisms of the VDR for whether there could be an association with bone mineral density (BMD) in relation to bone...

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PMID: 14530911
DOI: 10.1007/s00198-003-1501-5

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