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Article

A multi-functional organelle mitochondrion is involved in cell death, proliferation and disease.

Current medicinal chemistry - 1 Dec 2003

Ohta Shigeo

Abstract excerpt

The mitochondrion, long considered an organelle specific to energy metabolism, is in fact multi-functional and involved in many diseases. Mitochondrial DNA accumulates somatic mutations during aging, the progression of cancer and diabetes. Most cancer cells contain homoplasmic mutations in the mi...

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PMID: 14529464
DOI: 10.2174/0929867033456440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14529464-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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