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Article

A majority of fragile X males with methylated, full mutation alleles have significant levels of FMR1 messenger RNA.

Journal of medical genetics - 1 Jul 2001

Tassone F, Hagerman R J, Taylor A K, Hagerman P J

Abstract excerpt

FMR1 mRNA levels were determined in peripheral blood leucocytes for 48 fragile X males with methylated, full mutation alleles that are resistant to cleavage by methylation sensitive enzymes. Using quantitative (fluorescence) RT-PCR, we observed that more than half of these males produce FMR1 mRNA, with some mRNA levels approaching those found in normal subjects. In none of the samples analysed was there any...

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Share to DNA Methylation
Share to Fragile X Mental Retardation Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fragile X Syndrome

Share to Gene Silencing

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Source

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Identifiers

PMID: 11432964
DOI: 10.1136/jmg.38.7.453
PMCID: PMC1757182

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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