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Article

Detection of mutations in RET proto-oncogene codon 634 through double tandem hybridization.

Molecular biotechnology - 1 Oct 2003

Maldonado-Rodríguez Rogelio, Espinosa-Lara Mercedes, Barrera-León Oscar, Colin-Tovar Carmen, González-Yebra Beatriz, Salcedo-Vargas Mauricio, Santiago-Hernández J Carlos, Méndez-Tenorio Alfonso, Beattie Kenneth L

Abstract excerpt

We developed a procedure to detect the 7 point mutations at Cys634 of the proto-oncogene RET, which is responsible for medullary thyroid carcinoma (MTC). Genomic DNA was prepared from blood samples obtained from normal and MTC-affected individuals belonging to a family with a history of the disease. The RET genotype for each individual was first established by performing restriction and sequencing analyses....

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Identifiers

PMID: 14526122
DOI: 10.1385/MB:25:2:113

Genes

RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detection of mutations in RET proto-oncogene codon 634 through double tandem hybridization.PMID 14526122Read ↗

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