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Article

Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia

7 Oct 2003

Abstract excerpt

We obtained a global view of gene expression in both cell lines and pediatric acute lymphoblastic leukemia (ALL) samples that harbor one of several selected chromosomal abnormalities. When the cell lines were studied alone, we found that these chromosomal abnormalities were associated with the predominant variation in transcriptional programs across the set of cell lines studied. When cell lines and clinical...

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PMID: 14525776
DOI: 10.1182/blood-2003-05-1518

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