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Article

Etiopathogenesis of Graves' disease.

Neuro endocrinology letters - 1 Jan 2000

Karasek Michal, Lewinski Andrzej

Abstract excerpt

Graves' disease is an autoimmune disorder, caused by thyroid-stimulating antibodies, which bind to and activate the thyrotropin receptor on thyroid cells, inducing the synthesis and release of thyroid hormones. It is a polygenic and multifactorial disease that develops as a result of complex interaction between genetic susceptibility and environmental and/or endogenous factors. Graves' disease differs from other...

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PMID: 14523350

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