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Article

Androgen regulation of the human FERM domain encoding gene EHM2 in a cell model of steroid-induced differentiation.

Biochemical and biophysical research communications - 17 Oct 2003

Chauhan Sanjay, Pandey Ritu, Way Jeffrey F, Sroka Thomas C, Demetriou Manolis C, Kunz Susan, Cress Anne E, Mount David W, Miesfeld Roger L

Abstract excerpt

We have developed a cell model to investigate steroid control of differentiation using a subline of HT1080 cells (HT-AR1) that have been engineered to express the human androgen receptor. Dihydrotestosterone (DHT) treatment of HT-AR1 cells induced growth arrest and cytoskeletal reorganization that was associated with the expression of fibronectin and the neuroendocrine markers chromogranin A and neuron-specific...

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Identifiers

PMID: 14521927
DOI: 10.1016/j.bbrc.2003.08.147
PMCID: PMC2740477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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