Article
[2-methoxyestradiol induces p53 independent apoptosis in pancratic carcinoma and inhibits growth of lung metastasis].
Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress - 1 Jan 1998
Schumacher G, Kataoka M, Roth J A, Mukhopadhyay T
Abstract excerpt
2-methoxyestradiol (2-ME) is able to inhibit growth of certain tumors. We were interested in studying this effect of 2-ME on pancreatic cancer. In three out of four cell lines, 2-ME induced 50-90% growth inhibition after 48 hours treatment with 2 microM 2-ME. TUNEL staining for apoptosis revealed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.