Article
Yeast as a model host to study replication and recombination of defective interfering RNA of Tomato bushy stunt virus.
Virology - 15 Sept 2003
Panavas Tadas, Nagy Peter D
Abstract excerpt
Defective interfering (DI) RNA associated with Tomato bushy stunt virus (TBSV), which is a plus-strand RNA virus, requires p33 and p92 proteins of TBSV or the related Cucumber necrosis virus (CNV), for replication in plants. To test if DI RNA can replicate in a model host, we coexpressed TBSV DI RNA and p33/p92 of CNV in yeast. We show evidence for replication of DI RNA in yeast, including (i) dependence on p33...
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