Article
BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: potential therapeutic targets.
The American journal of pathology - 1 Oct 2003
Calhoun Eric S, Jones Jessa B, Ashfaq Raheela, Adsay Volkan, Baker Suzanne J, Valentine Virginia, Hempen Paula M, Hilgers Werner, Yeo Charles J, Hruban Ralph H, Kern Scott E
Abstract excerpt
The recognition of biologically distinct tumor subsets is fundamental to understanding tumorigenesis. This study investigated the mutational status of the serine/threonine kinase BRAF and the cyclin E regulator FBXW7 (CDC4, FBW7, AGO, SEL10) related to two distinct pancreatic carcinoma subsets: t...
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