Article
Effect of adenine metabolites on survival of Drosophila melanogaster of low xanthine dehydrogenase activity.
Comparative biochemistry and physiology. B, Comparative biochemistry - 1 Oct 1992
Ho Y K, Guthrie M J, Clifford A J, Ho C C
Abstract excerpt
1. Low xanthine dehydrogenase (LXD) mutant Drosophila melanogaster were fed 0.2% adenine for 7 generations, no adenine for the next 2 generations (relaxed) and 0.2% adenine again for the next 3 generations (rechallenged) to obtain adenine-resistant lines of Drosophila (LXD-adenine). Flies grown without adenine served as LXD-controls. 2. Purines ranked as follows; adenine > adenosine > AMP > inosine > IMP in...
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