Effect of adenine metabolites on survival of Drosophila melanogaster of low xanthine dehydrogenase activity.

doi:10.1016/0305-0491(92)90313-g

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Article

Effect of adenine metabolites on survival of Drosophila melanogaster of low xanthine dehydrogenase activity.

Comparative biochemistry and physiology. B, Comparative biochemistry - 1 Oct 1992

Ho Y K, Guthrie M J, Clifford A J, Ho C C

Abstract excerpt

1. Low xanthine dehydrogenase (LXD) mutant Drosophila melanogaster were fed 0.2% adenine for 7 generations, no adenine for the next 2 generations (relaxed) and 0.2% adenine again for the next 3 generations (rechallenged) to obtain adenine-resistant lines of Drosophila (LXD-adenine). Flies grown w...

Topics

Adenine
Animals
Drosophila melanogaster
Female
Male
Mutation
Purine-Pyrimidine Metabolism, Inborn Errors
Purines
Structure-Activity Relationship
Xanthine Dehydrogenase

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