Article
Expression of O6-methylguanine--DNA methyltransferase and uracil--DNA glycosylase in human placentae from smokers and non-smokers.
Carcinogenesis - 1 Oct 1992
Slupphaug G, Lettrem I, Myrnes B, Krokan H E
Abstract excerpt
DNA repair capacity is likely to be a critical factor in mutagenesis and carcinogenesis, as well as for the response to some cytostatics. We have studied inter- and intra-individual variation in the activities of O6-methylguanine--DNA methyltransferase (O6-MT) and uracil--DNA glycosylase (UDG) in...
Topics
- DNA Glycosylases
- DNA Repair
- Enzyme Induction
- Female
- Genetic Variation
- Humans
- Methyltransferases
- N-Glycosyl Hydrolases
- O(6)-Methylguanine-DNA Methyltransferase
- Placenta
- Pregnancy
- RNA, Messenger
- Smoking
- Uracil-DNA Glycosidase