Article
Activation and detection of (pro)mutagenic chemicals using recombinant strains of Streptomyces griseus.
Applied biochemistry and biotechnology - 1 Jan 1992
Buchholz S E, Omer C A, Viitanen P V, Sariaslani F S, Stahl R G
Abstract excerpt
Two recombinant strains of Streptomyces griseus have been developed to report on the activation of promutagenic chemicals. This activation is monitored by reversion of the bacterial test strains to a kanamycin-resistant phenotype. Strain H69 detects point mutations and was reverted at an increased frequency by acetonitrile, 2-aminoanthracene, 1,2-benzanthracene, benzidine, benzo(a)pyrene,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.