Article
Early regional specification for a molecular neuronal phenotype in the rat neocortex.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 1992
Arimatsu Y, Miyamoto M, Nihonmatsu I, Hirata K, Uratani Y, Hatanaka Y, Takiguchi-Hayashi K
Abstract excerpt
The timing of neocortical regional specification was examined using a monoclonal antibody, designated PC3.1, that binds a 29-kDa polypeptide and recognizes a neuronal subpopulation located in the lateral but not dorsomedial neocortex in the rat. When lateral cortical tissue fragments at embryonic days 12 and 16 were maintained in an organotypic culture system, a substantial number of neurons became...
Topics
- Animals
- Antibodies, Monoclonal
- Cells, Cultured
- Cerebral Cortex
- Immunohistochemistry
- Mice
- Mice, Inbred BALB C
- Nerve Tissue Proteins
- Neurons
- Organ Culture Techniques
- Phenotype