Characterization of an angiosarcoma-inducing mutation in the erbB oncogene.

Article

Characterization of an angiosarcoma-inducing mutation in the erbB oncogene.

Oncogene - 1 Oct 1992

Robinson H L, Tracy S E, Nair N, Taglienti-Sian C, Gamett D C

Abstract excerpt

The erbB oncogenes of two transducing viruses that arose in chicken 5005 have been molecularly characterized. One of these viruses, AEV-5005, caused erythroblastosis. The other, AAV-5005, caused angiosarcoma. Both viruses had identical 5' junctions of viral and host sequences, indicating that bot...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chickens
Cloning, Molecular
ErbB Receptors
Gene Deletion
Hemangiosarcoma
Molecular Sequence Data
Mutation
Phosphorylation
Proto-Oncogene Proteins
Proto-Oncogenes

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