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Article

Characterisation of dystrophin in fetuses at risk for Duchenne muscular dystrophy.

Journal of the neurological sciences - 1 Aug 1992

Clerk A, Sewry C A, Dubowitz V, Strong P N

Abstract excerpt

Dystrophin, the product of the Duchenne muscular dystrophy (DMD) gene, was studied in muscle from 16 human fetuses at risk for the disease. Eleven high risk (greater than 95% probability) and 5 low-risk (less than 25% probability) fetuses were studied with antibodies raised to different regions of the protein. All low-risk fetuses showed a similar pattern to that of normal fetuses of a comparable age: using...

Topics

Blotting, Western
Dystrophin
Female
Fetus
Humans
Immunohistochemistry
Muscles
Muscular Dystrophies
Phenotype
Pregnancy
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1403002
DOI: 10.1016/0022-510x(92)90116-3

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1403002-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Characterisation of dystrophin in fetuses at risk for Duchenne muscular dystrophy.PMID 1403002Read ↗

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