Article
Cloning of human AMP deaminase isoform E cDNAs. Evidence for a third AMPD gene exhibiting alternatively spliced 5'-exons.
The Journal of biological chemistry - 15 Oct 1992
Mahnke-Zizelman D K, Sabina R L
Abstract excerpt
Higher eukaryotes express multiple isoforms of AMP deaminase (EC 3.5.4.6). In humans, four AMP deaminase variants, termed M (muscle), L (liver), E1, and E2 (erythrocyte) can be distinguished by a variety of biochemical and immunological criteria. Previous molecular studies have reported two genes...
Topics
- AMP Deaminase
- Alternative Splicing
- Amino Acid Sequence
- Base Sequence
- Blotting, Southern
- Cloning, Molecular
- DNA
- DNA, Neoplasm
- Erythrocytes
- Exons
- Genetic Variation
- Genomic Library
- Humans
- Introns
- Isoenzymes
- Leukemia-Lymphoma, Adult T-Cell
- Liver
- Molecular Sequence Data