Article
Molecular characterization and expression patterns of AMP deaminase1 (AMPD1) in porcine skeletal muscle.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology - 1 Oct 2008
Wang Linjie, Mo Xiaoyu, Xu Yongjie, Zuo Bo, Lei Minggang, Li Fenge, Jiang Siwen, Deng Changyan, Xiong Yuanzhu
Abstract excerpt
AMPD1 is the muscle-specific form of the AMPD multigene families in mammals and plays an important role in the purine nucleotide cycle and energy metabolism in skeletal muscle. In this study, we cloned and characterized AMPD1 from Sus scrofa muscle. The promoter of porcine AMPD1 contained several putative muscle-specific transcription factor binding sites (E box, myogenin, MEF2, Spl-CTF/NF-l), one RORalpha2...
Topics
- AMP Deaminase
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cloning, Molecular
- DNA Primers
- Female
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Enzymologic