Article
Autosomal dominant mouse cataract (Lop-10). Consistent differences of expression in heterozygotes.
Investigative ophthalmology & visual science - 1 Oct 1992
Runge P E, Hawes N L, Heckenlively J R, Langley S H, Roderick T H
Abstract excerpt
The clinical and histologic features are reported of an autosomal dominant mouse cataract that was first observed as a new mutation in a cross between BALB/cJ and AKR/J. In the homozygous state, the eyes were microphthalmic, and a dense white cataract was present when the eyes opened at day 12. Histologic changes were apparent from birth and as early as 18 days' gestation. Liquefaction started by day 4, and...
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