Article
Surgical stress impairs natural killer cell programming of tumor for lysis in patients with sarcomas and other solid tumors.
Cancer - 15 Oct 1992
Pollock R E, Lotzová E, Stanford S D
Abstract excerpt
BACKGROUND: Natural killer (NK) cells may provide a first line of defense against the metastatic implantation of circulating tumor emboli. Because tumor emboli are discharged systemically in patients undergoing solid tumor resection, it is important to determine the nature of surgical-stress impairment of perioperative NK cell cytotoxic function. METHODS: The authors studied 85 patients undergoing surgical...
Topics
- Cell Separation
- Cytotoxicity Tests, Immunologic
- Cytotoxicity, Immunologic
- Humans
- Killer Cells, Natural
- Phenotype
- Stress, Physiological
- Surgical Procedures, Operative
- T-Lymphocytes, Regulatory