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Article

Detection of variation in the ribosomal RNA gene clusters by a modified fluorescence in situ hybridization method.

The Japanese journal of human genetics - 1 Jun 1992

Fukuyama R, Shimizu N

Abstract excerpt

Physical mapping of genes by fluorescence in situ hybridization (FISH) has become routine using fluorescein isothiocyanate (FITC) for probe detection and propidium iodide (PI) for chromosome staining. We have modified this conventional FISH method in a way that utilizes Texas red (TR) for signal detection and quinacrine mustard (QM) for chromosome banding. Using this Texas red and quinacrine (TRQ) method, we were...

Topics

Cell Line
Diploidy
Fluorescent Dyes
Genetic Variation
Humans
In Situ Hybridization
Lymphocytes
Microscopy, Fluorescence
Multigene Family
Quinacrine
Xanthenes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

rRNA Operon

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Identifiers

PMID: 1391969
DOI: 10.1007/BF01899735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1391969-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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