Characterization of a class 3 tyrosine kinase.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Characterization of a class 3 tyrosine kinase.

Oncogene - 1 May 1992

Howard O M, Dean M, Young H, Ramsburg M, Turpin J A, Michiel D F, Kelvin D J, Lee L, Farrar W L

Abstract excerpt

In an effort to identify unique tyrosine kinases found in human leukemia cell lines, we utilized polymerase chain reaction (PCR) technology and degenerate oligonucleotide primers to produce a cDNA library of kinase catalytic domains found in the human monocytic cell line AML-193. This search yielded a member of the class 3 tyrosine kinases closely related to the murine kinase FD-22. Previous work has identified...

Topics

Alleles
Amino Acid Sequence
Blotting, Northern
Blotting, Southern
Chromosome Mapping
Chromosomes, Human, Pair 1
Gene Frequency
Gene Library
Humans
Hybrid Cells
Leukemia, Monocytic, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Protein-Tyrosine Kinases

RNA

Sequence Homology, Nucleic Acid

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1373877

Genes

JAK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1373877-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Characterization of a class 3 tyrosine kinase.PMID 1373877Read ↗

Identification of a constitutively active mutant of JAK3 by retroviral expression screening.Semantic proximity Read ↗

JAK3: expression and mapping to chromosome 19p12-13.1.Semantic proximity Read ↗

A Kinase-deficient Splice Variant of the Human JAK3 Is Expressed in Hematopoietic and Epithelial Cancer CellsSemantic proximity Read ↗

The human myeloid cell nuclear differentiation antigen gene is one of at least two related interferon-inducible genes located on chromosome 1q that are expressed specifically in hematopoietic cellsSemantic proximity Read ↗

Identification and Characterization of a Novel Cytokine-inducible Nuclear Protein from Human Endothelial CellsSemantic proximity Read ↗

Cloning and expression of the human myeloid cell nuclear differentiation antigen: Regulation by interferon αSemantic proximity Read ↗

Molecular genetics of human leukemias: new insights into therapy.Semantic proximity Read ↗

High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.