The gene encoding hypoxanthine-guanine phosphoribosyltransferase as target for mutational analysis: PCR cloning and sequencing of the cDNA from the rat.

doi:10.1016/0027-5107(92)90178-5

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Article

The gene encoding hypoxanthine-guanine phosphoribosyltransferase as target for mutational analysis: PCR cloning and sequencing of the cDNA from the rat.

Mutation research - 1 Apr 1992

Jansen J G, Vrieling H, van Zeeland A A, Mohn G R

Abstract excerpt

In this paper, the cloning and nucleotide sequence of the cDNA of the rat gene coding for hypoxanthine-guanine phosphoribosyltransferase (hprt) is reported. Knowledge of the cDNA sequence is needed, among other reasons, for the molecular analysis of hprt mutations occurring in rat cells, such as...

Topics

Amino Acid Sequence
Animals
Base Sequence
DNA
Hypoxanthine Phosphoribosyltransferase
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Rats
Rats, Inbred Strains

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