Article
Applications of ultrafast HPLC to process development of recombinant DNA-derived proteins.
Biotechnology progress - 1 Jan 2000
Olson K C, Gehant R L
Abstract excerpt
The application of ultrafast HPLC to the development of recovery processes for proteins produced by recombinant DNA technology has been explored using wide-pore HPLC resins and instrumentation designed for rapid analysis. High-resolution analysis of complex samples was achieved with a total analysis time of less than 5 min from injection to injection. Fractions collected during preparative chromatography were...
Topics
- Biotechnology
- Chromatography, High Pressure Liquid
- Chromatography, Ion Exchange
- DNA, Recombinant
- Genetic Variation
- Protein Processing, Post-Translational
- Recombinant Proteins