Article
Facilitation of horizontal transfer of antimicrobial resistance by transformation of antibiotic-induced cell-wall-deficient bacteria.
Medical hypotheses - 1 Oct 2003
Woo P C Y, To A P C, Lau S K P, Yuen K Y
Abstract excerpt
It is universally accepted that the use of antibiotics will lead to antimicrobial resistance. Traditionally, the explanation to this phenomenon was random mutation and horizontal gene transfer and amplification by selective pressure. Subsequently, a second mechanism of antibiotic-induced antimicrobial resistance acquisition was proposed, when Davies et al. discovered that genes encoding antimicrobial resistance...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.