Article
Polymorphism of class I alcohol dehydrogenase in French, Vietnamese and Niger populations: genotyping by PCR amplification and RFLP analysis on dried blood spots.
Annales de genetique - 1 Jan 1992
Iron A, Groppi A, Fleury B, Begueret J, Cassaigne A, Couzigou P
Abstract excerpt
The polymorphism of human alcohol dehydrogenase (ADH) can contribute to the explanation of the important ethnic differences towards alcohol metabolism. Its assessment at the genomic DNA level with a procedure, excluding labelled probes, consisting of PCR (Polymerase chain reaction) amplification on dried blood spots and analysis of allele-specific RFLP (Restriction fragment length polymorphism) profiles, is well...
Topics
- Alcohol Dehydrogenase
- Alcohols
- Alleles
- Blood
- France
- Gene Amplification
- Genotype
- Humans
- Niger
- Nucleic Acid Amplification Techniques
- Polymerase Chain Reaction
