Article
The Epstein-Barr virus encoded membrane protein (LMP) induces phenotypic changes in epithelial cells.
Virchows Archiv. B, Cell pathology including molecular pathology - 1 Jan 1992
Niedobitek G, Fahraeus R, Herbst H, Latza U, Ferszt A, Klein G, Stein H
Abstract excerpt
The Epstein-Barr virus (EBV)-encoded membrane protein, LMP, is expressed in a proportion of undifferentiated nasopharyngeal carcinomas (NPC). Previous studies have shown that the transfection of the gene encoding LMP into a human keratinocyte line, RHEK-1, induces morphological alterations and a...
Topics
- Antigens, CD
- Antigens, Neoplasm
- Antigens, Surface
- Antigens, Viral
- Biomarkers
- Carcinoma
- Cell Line
- DNA, Viral
- Epithelium
- Humans
- Keratinocytes
- Membrane Glycoproteins
- Mucin-1
- Nasopharyngeal Neoplasms
- Neoplasm Proteins
- Phenotype
- Transfection
- Viral Matrix Proteins