Article
The Epstein-Barr virus encoded membrane protein (LMP) induces phenotypic changes in epithelial cells.
Virchows Archiv. B, Cell pathology including molecular pathology - 1 Jan 1992
Niedobitek G, Fahraeus R, Herbst H, Latza U, Ferszt A, Klein G, Stein H
Abstract excerpt
The Epstein-Barr virus (EBV)-encoded membrane protein, LMP, is expressed in a proportion of undifferentiated nasopharyngeal carcinomas (NPC). Previous studies have shown that the transfection of the gene encoding LMP into a human keratinocyte line, RHEK-1, induces morphological alterations and a reduced expression of cytokeratins. We have analyzed immunophenotypic changes in the RHEK-1 line following...
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