Article
Genetic diversity of penicillin-resistant Neisseria meningitidis.
The Journal of infectious diseases - 1 Jul 1992
Campos J, Fusté M C, Trujillo G, Sáez-Nieto J, Vázquez J, Lorén J G, Viñas M, Spratt B G
Abstract excerpt
The genetic relatedness of 42 penicillin-resistant Neisseria meningitidis isolates obtained during a 2-year period from a single hospital was studied by multilocus enzyme electrophoresis and by restriction fragment length polymorphism (RFLP) analysis of penicillin-binding protein (PBP) 2 genes. The PBP 2 genes of 7 susceptible strains gave identical RFLP profiles. Sixteen different PBP 2 RFLP profiles were found...
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