Article
Linkage analysis and long QT syndrome. Using genetics to study cardiovascular disease.
Circulation - 1 Jun 1992
Keating M
Abstract excerpt
BACKGROUND: Recombinant DNA technologies have facilitated the development of a set of polymorphic DNA markers covering the human genome. General linkage analysis in families predisposed to inherited disease is now feasible. Linkage analysis can help identify a disease gene even when relatively little is known about the disorder. METHODS AND RESULTS: Using this approach, we have identified linkage between a gene...
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